On April 27th, Professor Li Weidong, dean of the School of Life Science and Engineering of Southwest Jiaotong University, delivered an academic report entitled "Bietic Full Synthesis Research of Several Natural Drug molecules" in conference Room 203. More than 40 representatives of teachers and students of the college attended the meeting.
In the academic report, Professor Li Weidong first introduced the history of full synthesis of natural products, and then introduced his research group on bionic carbon positive ions and its full synthesis of important plant-derived drugs such as tricuaxin (Cephalotaxine), lily (diterpenoid Andrographolides).Around the bionic synthesis process of tricine, we detail the basic skeleton synthesis through six steps and three fragments.In the report, Li Weidong explained the explanation and showed the charm of total synthesis, which not only made the teachers and students feel Professor Li Weidong's love for full synthesis, but also aroused the strong interest of the teachers and students present.
In the evaluation stage, Professor Lei Xinxiang exchanged his views on the current situation of the full synthesis of natural products.Professor Li believes that with the development of synthetic technology, domestic scientists will have more and more research on flexible natural product molecules, and will take the full synthesis of erythromycin as an example for further explanation.
Li Weidong is now the professor and doctoral supervisor of the School of Life Science and Engineering, Southwest Jiaotong University, under Professor E. J. Corey, a Nobel Prize winner in Chemistry.Since returning to China in 1998, he has taught in Lanzhou University and Nankai University successively.In 1999, the "Changjiang Scholars" of the Ministry of Education was the winner of the National Outstanding Youth Fund in 2000.Mainly engaged in the teaching and scientific research of synthetic organic chemistry, specializing in the full synthesis of natural products and natural drugs, committed to the development of new chemical synthesis strategies of natural products with important physiological activities and the development of synthetic organic chemistry new reactions, new methods of research and application.
