Date of birth: 1974-09
Ethnic group:Han nationality
Title and post: Professor, Director of the Department of Chemical Biology
Subject major: Genetic engineering pharmaceuticals and ion channel pharmacology
E-mail: yinshijinyf@163.com
Education and research experience
1993.9-1998.7: Medical School of Wuhan University, China, Bachelor's degree in clinical medicine
1998.9-2001.7: Medical School of Wuhan University, China, Master's degree in neurophysiology
2001.7 to now: Pharmacy College of South-Central University For Nationalities, China, Professor, Director of the Department of Chemical Biology
2006.9-2009.6: Virology and Molecular Oncology Lab State Key Laboratory of Virology, Life Sciences College of Wuhan University, China, Doctor's degree in Microbiology
2011.6-2014.5: Department of pharmacology, School of medicine, Texas State University, USA, Postdoctor
2014.5-2014.8: Department of Anesthesiology at the Washington University in St.
Louis, USA, Postdoctor
Research Publications
（1）Jing Feng, Jialie Luo, Madison R. Mack, Pu Yang, Feng Zhang, Guan Wang, Xuan Gong, Tao Cai, Zhinan Mei, Brian Kim, Shijin Yin*, Hongzhen Hu. The antimicrobial peptide hBD2 promotes itch through Toll-like receptor 4 signaling in mice. Journal of Allergy and Clinical Immunology, 2017, 140(3):885-888. (SCI，IF 13.06, *Corresponding author).
（2）Zou Y, Zhang F, Li Y, Wang Y, Li Y, Long Z, Shi S, Shuai L, Liu J, Di Z, Shijin Yin*. Cloning, expression and identification of KTX-Sp4, a selective Kv1.3 peptidic blocker from Scorpiops pococki. Cell & Bioscience. 2017, 7:60.（SCI, IF 3.29, *Corresponding author).
（3）Feng J, Yang P, Mack MR, Dryn D, Luo J, Gong X, Liu S, Oetjen LK, Zholos AV, Mei Z, Shijin Yin, Kim BS, Hu H. Sensory TRP channels contribute differentially to skin inflammation and persistent itch. Nat Commun. 2017, 8(1):980. (SCI，IF 12.124).
（4）Luo J, Bavencoffe A, Yang P, Feng J, Shijin Yin, Qian A, Yu W, Liu S, Gong X, Cai T, Walters ET, Dessauer CW, Hu H. Zinc inhibits TRPV1 to alleviate chemotherapy-induced neuropathic pain. J Neurosci. 2018, 38(2):474-483. (SCI，IF 5.988)
（5）Luo J, Feng J, Yu G, Yang P, Mack MR, Du J, Yu W, Qian A, Zhang Y, Liu S, Shijin Yin, Xu A, Cheng J, Liu Q, O'Neil RG, Xia Y, Ma L, Carlton SM, Kim BS, Renner K, Liu Q, Hu H. Transient receptor potential vanilloid 4-expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch. J Allergy Clin Immunol. 2017, pii: S0091-6749(17)31098-9. doi: 10.1016. (SCI，IF 13.06).
（6）Kim S, Barry DM, Liu XY, Shijin Yin, Munanairi A, Meng QT, Cheng W, Mo P, Wan L, Liu SB, Ratnayake K, Zhao ZQ, Gautam N, Zheng J, Karunarathne WK, Chen ZF. Facilitation of TRPV4 by TRPV1 is required for itch transmission in some sensory neuron populations. Sci Signal. 2016,19;9(437):ra71. (SCI，IF 7.359)
（7）Shijin Yin，Yanning Qiu，Zhaohui Pan，Shaobin Li，Zhiyong Di . Chaerilus pseudoconchiformus sp. nov., a new species found in Xizang, and anupdated key of the chaerilid scorpions from China (Scorpiones:Chaerilidae)，ZooKeys，2015，495：41-51.（SCI）
（8）Shijin Yin，Yunfeng Zhang，Zhaohui Pan，Shaobin Li，Zhiyong Di ，Scorpiops ingens sp.nov.,found in Xizang, and an updated key of Scorpions fromChina(Scorpiones:Euscorpidae, Scorpiopinae)，ZooKeys，2015，495：53-61。（SCI）
（9）Shijin Yin*，Qinglan Hu，Jialie Luo，Yuxin Li，Chunlan Lu，XuanChen，Hongzhen Hu. Loureirin B, an essential component of Sanguis Draxonis,inhibits Kv1.3 channel and suppresses cytokine release from Jurkat T cells，Cell & Bioscience，2014，4：78。（SCI, IF 3.29, *Corresponding author）
（10）Shijin,Yin*, Jialie Luo, Aihua Qian, Weihua Yu, Hongzhen Hu. LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels. Br J Pharmacol. 2014,171(6):1510-20 (SCI二区，IF 5.06, *Corresponding author)
（11）Shijin,Yin, Jialie Luo, Aihua Qian, Junhui Du, Qing Yang, Shentai Zhou, Weihua Yu, Guangwei Du, Richard B. Clark, Edgar T. Walters, Susan M. Carlton, and Hongzhen Hu. Retinoids activate the irritant receptor TRPV1 and produce sensory hypersensitivity. The Journal of Clinical Investigation, 2013, 8:1-11 (SCI, IF 13.21)
（12）Dai, Hui1、Shijin Yin1、Li, Tian、Cao, Zhijian、Ji, Yonghua、Wu, Yingliang、Li, Wenxin. Recombinant expression, purification, and characterization of scorpion toxin Bm alpha TX14. Protein Expression and Purification, 2012,82(2): 325-331.(SCI, Co-First author)
（13）Song Han1, Shijin Yin1, Hong Yi.Ste´phanie Mouhat, Su Qiu, Zhijian Cao, Jean-Marc Sabatier, Yingliang Wu, and Wenxin Li. Protein-Protein Recognition Control by ModulatingElectrostaticInteractions. J Proteome Res, 2010, 9(6):3118-25（SCI, IF 5.684, Co-First author）
（14）Shijin Yin., Jiang L., Yi H., Han S., Yang D.W., Liu M.L., Liu H., Cao Z.J., Wu Y.L. & Li W.X. Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels. J Proteome Res,2008, 7, 4890-4897.(SCI, IF 5.67)
（15）Shijin Yin; Hong, Y.; Yibao, M.; Zongyun, C.; Han, S.; Yingliang, W.; Zhijian, C.; Wenxin, L., Characterization of a new Kv1.3 channel-specific blocker, J123, from the scorpion Buthus martensii Karsch. Peptides, 2008，29（9）: 1514-20. (SCI，IF 2.86)
（16）Han, S1.; Yi, H1.; Shijin Yin1.; Chen, Z. Y.; Liu, H.; Cao, Z. J.; Wu, Y. L.; Li, W. X., Structural basis of a potent Peptide inhibitor designed for kv1.3 channel, a therapeutic target of autoimmune disease. J Biol Chem , 2008, 283, 19058-19065.(SCI, IF 5.7, Co-First author)
（17）Wu, W1.; Shijin Yin1.; Ma, Y.; Wu, Y. L.; Zhao, R.; Gan, G.; Ding, J.; Cao, Z.; Li, W., Molecular cloning and electrophysiological studies on the first K(+) channel toxin (LmKTx8) derived from scorpion Lychas mucronatus. Peptides, 2007, 28, 2306-2312.（SCI, IF 2.86，Co-First author）
